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目的观察了持续血液净化(continuous blood purification,CBP)治疗顽固性心衰的疗效。方法 88例顽固性心衰患者分为两组,A组50例,按照常规利尿、扩血管、强心和血管活性药物治疗,B组38例,进行CBP治疗,超滤量在每天1500~2500ml,连续进行3~10d。观察治疗7d后心衰控制情况和住院20d内死亡率。结果 A组患者心衰好转率26.00,20d内死亡率38.00,B组患者心衰好转率63.16,20d内死亡率18.42,组间比较差异均有统计学意义(P<0.05)。结论 CBP治疗的顽固性心衰疗效肯定,可以提高患者生存率。
Objective To observe the curative effect of continuous blood purification (CBP) on refractory heart failure. Methods A total of 88 patients with refractory heart failure were divided into two groups. Group A (n = 50) was treated with conventional diuretic, vasodilator, cardiotonic and vasoactive drugs. Group B (38 cases) received CBP. The ultrafiltration volume was 1500-2500ml per day , Continuous for 3 ~ 10d. Observed 7d after treatment of heart failure control and mortality within 20d hospitalization. Results In group A, the heart failure rate was 26.00 and the mortality rate was 38.00 in 20 days. The improvement rate of heart failure in group B was 63.16 and the death rate was 18.42 in 20 days. There was significant difference between the two groups (P <0.05). Conclusion CBP treatment of refractory heart failure positive effect, can improve patient survival.