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目的:分析血浆同型半胱氨酸(Hcy)、超敏C反应蛋白(hs-CRP)在急性心肌梗死(AMI)中的临床价值。方法:选择2014-03-2015-03在我院急诊科的AMI患者78例进行分析,分为急性ST段抬高型性心肌梗死组(STEMI组)33例,急性非ST段抬高型心肌梗死(NSTEMI组)45例,并选取对照组20例。根据治疗方法的不同分为急诊PCI组、溶栓组及保守治疗组,常规测定治疗前后Hcy及hs-CRP水平。结果:STEMI组及NSTEMI组的Hcy及hs-CRP显著高于对照组(P<0.01);急诊PCI治疗组及溶栓组较保守治疗组Hcy及hs-CRP水平下降(P<0.05),急诊PCI组及溶栓组Hcy及hs-CRP比较差异无统计学意义(P>0.05);AMI治疗后Hcy及hs-CRP水平较治疗前下降(P<0.01)。结论:血浆Hcy血症、hs-CRP显著升高患者AMI的可能性较大,可以作为AMI的预测因子,在临床中诊断价值较大。
Objective: To analyze the clinical value of plasma homocysteine (Hcy) and high sensitivity C-reactive protein (hs-CRP) in acute myocardial infarction (AMI). Methods: A total of 78 patients with acute myocardial infarction (AMI) in our emergency department from March 2014 to March 2015 were selected and divided into three groups: STEMI group (33 cases), acute non-ST segment elevation myocardial infarction 45 cases of infarction (NSTEMI group) and 20 cases of control group. According to the different treatment methods, the patients were divided into emergency PCI group, thrombolytic group and conservative treatment group. Hcy and hs-CRP levels were determined routinely before and after treatment. Results: The levels of Hcy and hs-CRP in STEMI group and NSTEMI group were significantly higher than those in control group (P <0.01). The levels of Hcy and hs-CRP in emergency PCI group and thrombolytic group were lower than those in conservative group (P <0.05) The levels of Hcy and hs-CRP in PCI group and thrombolytic group were not significantly different (P> 0.05). The levels of Hcy and hs-CRP in AMI group were lower than those before treatment (P <0.01). Conclusion: Hs-CRP in patients with plasma Hs-CRP significantly increased the possibility of AMI in patients with larger, can be used as a predictor of AMI in the clinical diagnosis of greater value.