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作者报告了用两种方法作静脉注射免疫球蛋白(IVIG)治疗新生儿感染的结果。第一种方法是把感染危险性增高的新生儿(白细胞计数5000/mm~3以下或25000/mm~3以上;血小板计数10万/mm~3以下,血清IgM水平>0.25g/1)随机分成两组,每组41例。一组只用抗生素治疗;另一组除用抗生素外再加用IVIG(早产儿用量为0.5g/天,共6天,足月产婴儿用量为1g/天,共6天)治疗。注射用免疫球蛋白含多种病毒和细菌抗体。结果表明,用IVIG治疗后血清IgG水平增高。早产儿经IVIG治疗6天后IgG水平平
The authors report the results of two methods of intravenous immunoglobulin (IVIG) treatment of neonatal infections. The first method is to randomize neonates (white blood cell count of 5000 / mm3 or less or 25000 / mm3 or more, platelet count of 100,000 / mm3 or less, and serum IgM level of> 0.25 g / 1) who are at increased risk of infection Divided into two groups, 41 cases in each group. One group was treated with antibiotics only; the other group was treated with IVIG in addition to antibiotics (0.5g / day for preterm infants, 6 days for full-term infants and 1g / day for full-term infants) for 6 days. Injectable immunoglobulins contain a variety of viral and bacterial antibodies. The results showed that serum IgG levels increased after treatment with IVIG. IgG levels in preterm infants after IVIG treatment for 6 days were normal