最近,在发达国家中结核病的发病率增加,导致了抗结核药物的广泛应用。由于大多数药物有抗药性,因此对活动性结核病人常联合使用抗结核药治疗。暴发性肝衰竭(从黄疸到肝性脑病时间少于15天)和亚暴发性肝衰竭(从黄疸到肝性脑病时间为16天～3个月)虽不常见,却是使用异烟肼的并 The recent increase in the incidence of tuberculosis in developed countries has led to the widespread use of anti-TB drugs. Because most drugs are drug-resistant, active tuberculosis is often combined with anti-TB drugs. Fulminant hepatic failure (less than 15 days from jaundice to hepatic encephalopathy) and sub-fulminant hepatic failure (from jaundice to hepatic encephalopathy, 16 days to 3 months) is uncommon but isoniazid and