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目的探讨早产儿血清降钙素原水平的变化及其临床意义。方法将2007年7月-2008年6月收住我院新生儿病房的28例早产儿及40例足月儿分为感染组与非感染组、早产儿非感染组与足月儿非感染组、早产儿感染组与早产儿非感染组,检测血清降钙素原。结果血清降钙素原水平:新生儿感染组高于非感染组,而早产儿非感染组与足月儿非感染组、早产儿感染组与早产儿非感染组则无显著性差异。结论血清降钙素原是新生儿全身细菌感染重要诊断指标,而早产儿变化不大;早产儿血清降钙素原水平与足月儿相近。
Objective To investigate the changes of serum procalcitonin levels in preterm infants and its clinical significance. Methods From July 2007 to June 2008, 28 cases of preterm infants and 40 term infants admitted to neonatal ward of our hospital were divided into infected group and non-infected group, non-infected preterm infants and non-infected infants , Premature infant infection group and non-infected preterm group, serum procalcitonin. Results Serum procalcitonin levels were higher in neonates with infection than in non-infected patients, but no significant difference was found between non-infected preterm children and non-infected infants in preterm infants and non-infected infants in premature infants. Conclusions Serum procalcitonin is an important diagnostic indicator of whole body bacterial infection in neonates, while there is little change in preterm infants. Serum procalcitonin levels in preterm infants are similar to those in term infants.