为解决疾病监测预警与应急处置系统实时获取分布异构监测数据的问题,本文分析疾病监测预警与应急处置业务产生数据交换环节,提出监测数据集成内容。从构建疾病预防控制数据中心的角度,提出按主题抽取数据、从语义和语法层面匹配数据、汇集整合数据的模式完成主题数据仓库建库,提出利用XML数据集交换格式、WSDL描述服务接口、SOAP消息传输协议、基于数据目录服务的请求/响应的模式实现增量更新主题数据仓库。 In order to solve the problem of real-time access to distributed heterogeneous monitoring data in disease surveillance, early warning and emergency response systems, this paper analyzes the data exchange aspects of disease surveillance and early warning and emergency response services and proposes the integrated monitoring data. From the perspective of building a CDC data center, this paper proposes that thematic data warehouse should be built by extracting data by theme, matching data at semantic and grammatical levels, and integrating data. The XML data set exchange format, WSDL description service interface, SOAP Message transfer protocol, based on the data directory service request / response model incremental update theme data warehouse.