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在家兔侧脑室内微量注射牛胰多肽能增加其糖耐量及血清胰岛素浓度。这种作用与牛胰多肽注射剂量有明显依从关系,并被预先皮下注射阿托品所部分阻断。结果提示,中枢给予牛胰多肽可能部分通过迷走神经途径增加血清胰岛素的释放而增加糖耐量。
Microinjection of bovine pancreatic polypeptide into lateral ventricle of rabbits can increase their glucose tolerance and serum insulin concentration. This effect and bovine pancreatic polypeptide dose significantly dependent on the relationship and was pre-subcutaneous injection of atropine partially blocked. The results suggest that the central administration of bovine pancreatic polypeptide may increase glucose tolerance partly by increasing the release of serum insulin via the vagus nerve pathway.