结膜下注射庆大霉素可在鼠、兔和人的结膜纤维母细胞内造成溶酶体的蓄积,电镜下溶酶体是颗粒状物质和多形的板层结构组成,与存在的复合脂质的样子相同。在动物除近端肾曲小管外,其它眼部组织包括由血运可达的细胞皆未受损。虽然本文未对人体肾脏作检查,但很可能有同样的病变。 Subconjunctival injection of gentamicin can cause lysosomal accumulation in conjunctival fibroblasts of mice, rabbits and humans. Under electron microscopy, lysosomes are composed of granular material and pleomorphic lamellar structures that interact with the presence of complex lipid The same quality. In addition to the proximal nephric tubules of animals, other ocular tissues, including those accessible to blood vessels, were intact. Although this article does not examine human kidneys, it is likely to have the same lesions.