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目的探讨经直肠二维超声、彩色多普勒联合弹性成像及超声造影综合评分预测前列腺癌(PCa)的价值。方法对71例经病理证实的前列腺病变进行回顾性分析。按照病理结果,将其分为2组。对其超声特征进行累加综合评分,其中二维超声、彩色多普勒、弹性成像及超声造影异常阳性发现均评为1分,阴性评分为0分。比较各综合评分值预测PCa的效能及受试者工作(ROC)曲线下面积。结果前列腺病变经直肠超声多项技术综合评分与其良恶性相关(R2=0.713,P<0.05)。综合评分0、1、2、3、4分预测PCa曲线下分别为:0.5、0.73、0.86、0.791、0.694。综合评分≥1、≥2、≥3分预测PCa ROC曲线下面积比较无明显统计学意义(P>0.05),但均大于综合评分=0分和4分ROC曲线下面积(P<0.05)。综合评分≥2分预测PCa的准确率较高(86%);综合评分4分预测PCa的阳性预测值为100%。结论超声多项技术综合评分≥2分有助于准确预测PCa。超声综合评分4分高度提示PCa。
Objective To investigate the value of transrectal two-dimensional ultrasound, color Doppler combined with elastography and contrast-enhanced ultrasound in predicting prostate cancer (PCa). Methods Retrospective analysis of 71 cases of pathologically confirmed prostate lesions. According to the pathological results, they were divided into two groups. The ultrasound features of the cumulative comprehensive score, including two-dimensional ultrasound, color Doppler, elastography and ultrasound findings were positive abnormal findings were rated as 1 points, negative score of 0 points. Each composite score was used to predict the efficacy of PCa and the area under the receiver operating (ROC) curve. Results Prostate lesions transrectal ultrasound combined with a number of technical and its benign and malignant (R2 = 0.713, P <0.05). Comprehensive score 0,1,2,3,4 points predicted PCa curve were: 0.5,0.73,0.86,0.791,0.694. The area under the PCa ROC curve was no statistically significant (P> 0.05), but both of them were greater than the area under the ROC curve (P <0.05) with the integrated score = 0 and 4 points. Comprehensive score ≥ 2 points higher accuracy of PCa prediction (86%); comprehensive score 4 points predicted PCa positive predictive value of 100%. Conclusion Ultrasound multiple comprehensive score ≥ 2 points help to accurately predict PCa. Ultrasound score 4 points high prompt PCa.