论文部分内容阅读
对2406例生殖异常患者进行D/G组染色体的着丝粒区(cen)和随体区(s)、副缢痕区(qh)、Y长臂(Yq)增加和9号臂间倒位等染色体异态性进行研究,发现异态率12.55％。自发流产、死胎、出生缺陷、无精子症、精子畸形、闭经、不孕患者染色体异态率分别为12.81％、9.18％、14.02％、14.18％、19.44％、8.92％、7.14％。各种类型染色体异态率inv(9)为1.08％、qh+1.83％、D/Gs+3.37％、D/G着丝粒增加0.37％、大Y11.45％。随着流产次数增加异态率亦明显增加,研究结果表明染色体异态与生殖异常有关。
In 2406 patients with genital abnormalities, the centromere (centroid) and the satellite region (s), qq, Y long arm (Yq) and the 9th arm inverted Heterochromic and other chromosomal research, found that abnormal rate of 12.55%. The rates of chromosome abnormalities in spontaneous abortion, stillbirth, birth defects, azoospermia, sperm deformity, amenorrhea and infertility were 12.81%, 9.18%, 14.02%, 14.18%, 19.44%, 8.92% and 7.14%, respectively. The rates of chromosome abnormalities inv (9) were 1.08%, qh + 1.83%, D / Gs + 3.37%, D / G centromere increased 0.37% and Y11.45% respectively. As the number of abortions increases, the morbidity rate also increases significantly. The results show that chromosomal abnormalities are related to reproductive abnormalities.