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帕金森病(Parkinson′s disease,PD)早期临床表现多不典型,早期诊断、早期神经保护治疗有可能延缓病程进展。经颅超声成像(transcranial sonography,TCS)是一种新型的非侵入性超声成像技术,可早期发现PD患者的黑质区回声增强这一特性,同时黑质回声与病程无关;根据其黑质回声的特征性改变,可对PD患者进行早期诊断。现结合近年国内外研究,对TCS在早期PD诊断中的价值进行综述。
Parkinson’s disease (Parkinson’s disease, PD) atypical early clinical manifestations, early diagnosis, early neuroprotective therapy may delay the course of progress. Transcranial sonography (TCS) is a new noninvasive ultrasound imaging technique that can early detect the enhancement of echogenicity in the substantia nigra of PD patients, while the substantia nigra echo has no relation with the duration of disease. According to its substantia nigra echo The characteristic changes in early diagnosis of PD patients. Now combined with recent years at home and abroad, the value of TCS in early diagnosis of PD are reviewed.