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目的探讨血液超滤在老年急性心肌梗死后合并心肾综合征中的应用。方法回顾性分析血液超滤在6例老年急性心肌梗死合并心肾综合征患者中的应用,比较超滤前后血生化指标、体重和心功能的变化。结果血液超滤后患者肾功能、电解质、碳酸氢根无明显变化(P>0.05),但尿酸、NT-proBNP在超滤后可见明显下降(P<0.05),心功能(killip分级)有所改善,左室舒张末期内径有所增加,射血分数有所下降(P<0.05),但在后期的随访中得以改善(P<0.05)。结论血液超滤治疗对老年急性心肌梗死后合并心肾综合征是一种迅速、安全、可靠、有效的抢救措施。
Objective To investigate the application of blood ultrafiltration in the treatment of elderly patients with acute myocardial infarction combined with cardiorenal syndrome. Methods The clinical application of blood ultrafiltration in 6 elderly patients with acute myocardial infarction complicated with cardiorenal syndrome was retrospectively analyzed. The changes of blood biochemical indexes, body weight and cardiac function before and after ultrafiltration were compared. Results No significant changes in renal function, electrolytes and bicarbonate were observed in patients after blood ultrafiltration (P> 0.05). However, the levels of uric acid and NT-proBNP were significantly decreased after ultrafiltration (P <0.05) The left ventricular end-diastolic diameter increased and the ejection fraction decreased (P <0.05), but was improved at the later follow-up (P <0.05). Conclusion Blood ultrafiltration therapy is a rapid, safe, reliable and effective treatment for elderly patients with acute myocardial infarction complicated with cardiorespiratory syndrome.