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结核性脑膜炎脑实质的结核病变(结核瘤),若累及脑动脉,致使脑血液循环障碍、血栓形成、供血不足,临床表现为偏瘫、抽搐、失语、意识障碍,伴随有脑膜刺激症状、发热等。国内外普遍采用的抗结核药并用激素治疗,效果不佳,遗留永久性瘫痪。为此,作者对传统治疗方法加以改进,结果报道如下。治疗方法与分组本组采用抗结核药 INH,PZA,SM, RFP 四联化疗并用激素为两组治疗的基础方法。分为两组:(一)溶解药物组 (1)尿激酶11例。尿激酶2万单位加入10%葡萄糖200ml,每日静滴,三天后改为1万单位连续每日静脉滴注,一个月或按需要延长应用时间。(2)玻璃酸酶150u,日二次或300u日一次肌注,连用1～2个月或按需要延长时间。配合应用头针运动区。
Tuberculous meningitis Brain parenchymal tuberculosis (tuberculoma), if involving the cerebral arteries, resulting in cerebral blood circulation disorders, thrombosis, hypoperfusion, clinical manifestations of hemiplegia, convulsions, aphasia, disturbance of consciousness, accompanied by meningeal irritation, fever Wait. Anti-TB drugs commonly used at home and abroad and hormone therapy, poor results, leaving permanent paralysis. To this end, the author to improve the traditional treatment methods, the results reported below. Treatment and grouping This group of anti-TB drugs INH, PZA, SM, RFP quadruple chemotherapy with hormones for the treatment of two basic methods. Divided into two groups: (a) dissolved drug group (1) urokinase in 11 cases. Urokinase 20,000 units added 10% glucose 200ml, intravenous infusion, three days later changed to 10,000 units of continuous daily intravenous infusion, a month or as needed to extend the application time. (2) hyaluronidase 150u, once a day or 300u day intramuscular injection, once every 1 to 2 months or as needed to extend the time. With the application of scalp sports area.