铜绿假单胞菌(铜绿)是重症感染和院内感染的主要病原菌。在我院近4年各类病原菌检测阳性标本中,除1996年分离率居第二外,其它年份均居首位。1993～1996年分别占临床分离菌的24.15%、23.48%、23.36%、20.56%。由于该菌对多种抗菌药低敏,选药难度较大。本文报告1993～1996年临床分离铜绿菌对常用抗菌药耐药状况及新用于该菌感染的环丙沙星、氧氟沙星MIC测定结果,以供临床选药参考。 Pseudomonas aeruginosa (patina) is the major pathogen of severe infections and nosocomial infections. In our hospital nearly 4 years of detection of various types of pathogens positive specimens, with the exception of 1996, the second highest rate of separation, other years ranked first. From 1993 to 1996, they accounted for 24.15%, 23.48%, 23.36% and 20.56% of clinical isolates respectively. As the bacteria on a variety of low-sensitivity antimicrobial agents, drug selection more difficult. This article reports from 1993 to 1996 clinical isolates of copper bacteria resistant to commonly used antibacterials and the new strain for the infection of ciprofloxacin, ofloxacin MIC determination results for clinical drug reference.