目的 :应用八峰氨基酸口服液对大鼠进行了传统致畸试验。观察本品是否引起母体毒性和胚胎毒性反应。方法 :设8g/kg、4g/kg、2 g/kg(相当临床的 30 ,15 ,6倍 ) 3个剂量组。浓鱼肝油为阳性对照物 ,自来水为阴性对照组。结果 :高、中剂量组孕鼠体重增长明显高于阴性对照组 ,高、中、低剂量组的胎鼠体重也都高于阴性对照组。结论 :八峰氨基酸口服液各剂量组对胎鼠有促进生长发育的作用 ,对孕鼠无母体毒性 ,无胚胎毒性和致畸作用 OBJECTIVE: To conduct traditional teratogenicity test in rats by using eight amino acid oral solution. Observe whether this product causes maternal toxicity and embryotoxicity. Methods: Three doses of 8g / kg, 4g / kg, 2g / kg (equivalent to 30, 15, and 6 times of clinical) Concentrated cod liver oil as a positive control, tap water as a negative control group. Results: The body weight of pregnant rats in high and middle dose groups was significantly higher than that of negative control group. The body weight of fetuses in high, medium and low dose groups were also higher than those in negative control group. Conclusion: The eight oral amino acid oral solution of each dose group on the fetal rat to promote growth and development of pregnant rats without maternal toxicity, embryo toxicity and teratogenic effects