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目的探讨奥扎格雷钠联合银杏叶治疗急性脑梗死的临床疗效。方法将50例急性脑梗死患者随机分为两组,研究组26例,应用奥扎格雷钠联合银杏叶治疗,对照组24例,应用复方丹参加低分子右旋糖酐治疗。观察15d。治疗前后采用神经功能缺损程度评定标准评定临床疗效。结果治疗15d末,研究组显效率84·6%,总有效率96·2%;对照组分别为41·7%,79·2%,两组比较差异有统计学意义(χ2=9·992、P<0·01)。两组神经功能缺损评分较治疗前均有极显著性下降(P<0·01),但研究组较对照组下降显著(P<0·05)。两组均未出现明显不良反应。结论奥扎格雷钠联合银杏叶治疗急性脑梗死疗效显著,安全性高,值得临床广泛推广应用。
Objective To investigate the clinical efficacy of ozagrel combined with ginkgo biloba in the treatment of acute cerebral infarction. Methods Fifty patients with acute cerebral infarction were randomly divided into two groups. The study group consisted of 26 patients treated with ozagrel and Ginkgo biloba, and 24 patients in the control group treated with compound Danshen plus low molecular weight dextran. Observation 15d. Before and after treatment with neurological deficit assessment criteria to assess the clinical efficacy. Results At the end of the 15th day of treatment, the effective rate of the study group was 84.6%, the total effective rate was 96.2%; the control group was 41.7% and 79.2% respectively, with significant difference between the two groups (χ2 = 9.992 , P <0.01). The score of neurological deficit in both groups was significantly lower than that before treatment (P <0.01), but the study group decreased significantly compared with the control group (P <0.05). No significant adverse reactions occurred in both groups. Conclusion Ozagrel sodium combined with Ginkgo biloba in the treatment of acute cerebral infarction significant effect, high safety, it is widely used in clinical practice.