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目的:观察强化口腔清洁对鼻咽癌患者放射性龋齿的预防效果。方法:选择接受根治性放疗鼻咽癌46例,随机分为观察组和对照组各23例,观察组采用以Bass刷牙为主体的加强型口腔清洁方法,对照组采用日常口腔清洁方法。对比观察两组放疗后第1年、第2年和第3年磨牙区牙冠新发生龋失补牙面数(DMFS)。结果:观察组放疗后第1年、第2年和第3年的新发DMFS分别为(2.70±0.95)个、(9.50±2.17)个和(20.70±2.06)个,对照组分别为(3.00±1.25)个、(14.60±2.32)个和(26.50±1.58)个;观察组第2年和第3年的新发DMFS显著低于对照组(P<0.05)。结论:强化口腔清洁能够有效降低鼻咽癌患者放射性龋齿发生率。
Objective: To observe the preventive effect of intensive oral cleaning on radiation-induced dental caries in patients with nasopharyngeal carcinoma. Methods: Forty-six patients with nasopharyngeal carcinoma undergoing radical radiotherapy were randomly divided into observation group (23 cases) and control group (23 cases). The patients in the observation group received intensive oral cleaning with Bass brushing as their main body, while the control group received daily oral cleaning. The number of dental malformations (DMFS) of the crowns in the first, second and third year after radiotherapy were compared between the two groups. Results: The new-onset DMFS were (2.70 ± 0.95), (9.50 ± 2.17) and (20.70 ± 2.06) in the observation group at the first year, the second year and the third year respectively. The control group were 3.00 ± 1.25), (14.60 ± 2.32) and (26.50 ± 1.58) respectively. The new-onset DMFS in the second and third years of the observation group was significantly lower than that of the control group (P <0.05). Conclusion: Intensive oral cleaning can effectively reduce the incidence of radioactive dental caries in patients with nasopharyngeal carcinoma.