黄色瘤是一种脂质代谢障碍性疾病,临床上表现为皮肤或肌腱有黄色或橙色的斑疹或结节,也可侵犯内脏器官,伴血脂异常及相应的临床症状。先天性家族性黄色瘤极为少见,我院曾收治两例同胞兄弟患者,现报道如下:病例报告例1:男,15岁,学生。出生时其母发现患儿骶尾部有数个1×2cm 大小桔黄色斑丘疹,以后随年龄增长逐渐增大增多,眼睑、 Yellow tumor is a lipid metabolism disorders, the clinical manifestations of the skin or tendon with yellow or orange spots or nodules, but also violations of internal organs, with dyslipidemia and the corresponding clinical symptoms. Congenital familial xanthoma is extremely rare, our hospital has admitted two siblings, are reported as follows: Case Report 1: male, 15 years old, student. Birth at the age of her mother found a few 1 × 2cm size of the sacrococcygeal orange macular rash, then gradually increased with age increased, the eyelids,