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为了观察睾酮替代治疗局限性前列腺癌外放射治疗后睾酮缺乏综合症的疗效。Morales A等选择了5例局限性前列腺癌外放射治疗后睾酮缺乏综合症患者,一旦前列腺特异抗原水平达到最低点,即予以睾酮替代治疗。睾酮替代治疗前平均睾酮水平为5.2(1.1～9.2)nmol/L,睾酮替代治疗14.5(6～27个月)月。最后一次随访,平均睾酮水平为17.6(8.5～32.4)nmol/L。5例患者中有1例有短暂的PSA水平增加,但所有患者PSA水平都没有高于1.5 ng/mL。所有患者的睾酮缺乏综合症的症状明显改善,4例潮热减少、疲劳减
In order to observe the efficacy of testosterone replacement therapy for post-testosterone deficiency syndrome after radiotherapy for localized prostate cancer. Morales A et al selected 5 patients with localized testosterone deficiency syndrome after external radiotherapy of prostate cancer who were given testosterone replacement therapy once the prostate specific antigen level reached its lowest point. Testosterone replacement therapy before the average testosterone levels 5.2 (1.1 ~ 9.2) nmol / L, testosterone replacement therapy 14.5 (6 to 27 months) months. At the last follow-up, the mean testosterone level was 17.6 (8.5-32.4) nmol / L. One of five patients had transient PSA levels increased, but none of the patients had PSA levels above 1.5 ng / mL. Symptoms of testosterone deficiency syndrome were significantly improved in all patients, with 4 cases of reduced hot flashes, reduced fatigue