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目的采取措施对米非司酮与安宫黄体酮在治疗女性围绝经期出现的功血疗效进行有效性研究。方法本组所研究的50例围绝经期功血患者是从医院收治的病例中选取出来的,她们的年龄在30-54岁之间。随机将这些患者划分成对照组与观察组,每一组有25例患者。对于对照组患者的治疗,主要采取安宫黄体酮药物的治疗。而对于观察组患者的治疗,主要采取米非司酮药物的治疗。对两组患者在服药期间与停止服药之后子宫内膜的厚度、阴道流血的状况以及性激素分泌状况的变化进行对比性分析与研究。结果经过一段时间的治疗与护理,两组患者的病情得到了有效的缓解,阴道流血状况得到有效控制。两组患者的子宫内膜厚度变薄,观察组患者所服用的药物在抑制子宫内膜增生与降低人体内P值、LH、FSH以及E2方面具有良好的治疗效果。观察组患者的治愈成功率高于对照组患者。结论利用米非司酮药物治疗女性围绝经期供血症状的疗效好于安宫黄体酮药物的治疗效果,具有极强的临床研究与应用价值。
Objective To take measures to study the effectiveness of mifepristone and nongon progesterone in treating peri-menopausal women’s dysfunctional uterine bleeding. Methods 50 cases of peri-menopausal dysfunctional uterine bleeding studied in this study were selected from the hospital cases, and their ages ranged from 30 to 54 years old. These patients were randomly divided into control and observation groups, each group of 25 patients. For the treatment of patients in the control group, mainly to the treatment of Andong progesterone drugs. For the treatment of patients in the observation group, the main treatment with mifepristone. The changes of endometrial thickness, vaginal bleeding and sex hormone secretion in the two groups during the medication and after stopping the medication were comparatively analyzed and studied. Results After a period of treatment and care, the two groups of patients have been effectively alleviated the condition, vaginal bleeding conditions have been effectively controlled. The endometrial thickness of the two groups of patients became thinner. The patients in the observation group had good curative effect in inhibiting endometrial hyperplasia, reducing P value, LH, FSH and E2 in the human body. The successful rate of cure in observation group was higher than that in control group. Conclusion The efficacy of mifepristone in the treatment of perimenopausal menstrual blood supply is better than that of Andhraine progesterone, which has strong clinical research and application value.