门脉高压是肝硬变的常见并发症。门脉高压引起胃粘膜损伤的机制被认为与胃血流动力学异常、内源性促胃酸分泌物质增多、内毒素血症等综合性因素导致胃粘膜屏障功能下降有关,近年来,我们对102例活动性肝硬变患者进行了胃镜检查,现将有关结果分析如下,以进一步探讨其发生机制。 1 资料与方法 从1994年12月～1996年12月,通过胃镜发现食道或食道伴胃底静脉曲张102例。男?8例(76.5％),女24例(23.5％),男:女为3.25∶1。年龄24～74岁,平均45±12岁。 Portal hypertension is a common complication of cirrhosis. Portal hypertension caused gastric mucosal injury mechanism is considered and gastric hemodynamic abnormalities, endogenous gastric acid secretion substances increased, endotoxemia and other comprehensive factors lead to decreased gastric mucosal barrier function, in recent years, we 102 Cases of active cirrhosis patients underwent endoscopy, the relevant results are analyzed below, to further explore its mechanism. 1 Materials and Methods From December 1994 to December 1996 102 cases of esophageal or esophageal varices were found by endoscopy. Male? 8 cases (76.5%), female 24 cases (23.5%), male: female 3.25: 1. Aged 24 to 74 years old, with an average of 45 ± 12 years old.