目的 研究某些因素与原发性肝癌之间的关系。方法 用Logistic回归方法分析306例原发性肝癌和627例人群对照某些因素在两者间的相对比值。结果 经年龄和受教育程度调整后发现:甲型肝炎(OR=14.66,95％CI:1.80～119.66)、乙型肝炎(OR=36.91,95％CI:16.84～80.87)、肝病和肝硬化(OR=25.47,95％CI:9.05～71.66)和其它肝胆疾病(OR=20.69,95％CI:4.79～89.42)与肝癌有密切关系;吸烟和饮酒均可增加肝癌危险性,并且两者具有相加作用。自我调节能力和适应环境能力差及长时间精神处于压抑状态增加肝癌危险性1.70～2.40倍。长期从事化工工作(OR=2.78,95％:1.24～6.21)、家族肿瘤史(OR=2.20,95％CI:1.38～3.51)均与肝癌发生有关。食物的凉、硬、干及重盐均可使肝癌危险性增加,而多食用豆制品及奶制品以及经常食用醋类具有预防肝癌的作用。结论 肝癌与既往肝病史、饮食、饮酒、吸烟及精神等因素有密切关系,多食用豆制品、奶制品及醋类具有预防肝癌发生的作用。 Objective To study the relationship between certain factors and primary liver cancer. Methods Logistic regression was used to analyze the relative ratios of some factors in 306 cases of primary liver cancer and 627 controls. Results After adjusting for age and education, it was found: Hepatitis A (OR=14.66, 95%CI: 1.80-119.66), Hepatitis B (OR=36.91, 95%CI: 16.84-80.87), Liver disease and Cirrhosis ( OR = 25.47, 95% CI: 9.05 - 71.66) and other hepatobiliary diseases (OR = 20.69, 95% CI: 4.79 - 89.42) are closely related to liver cancer; smoking and drinking can increase the risk of liver cancer, and both have Add effect. Poor self-regulatory ability and ability to adapt to the environment and prolonged mental stress are increasing the risk of liver cancer by 1.70 to 2.40 times. Long-term chemical work (OR = 2.78, 95%: 1.24 ~ 6.21), family history of cancer (OR = 2.20, 95% CI: 1.38 ~ 3.51) are all related to the occurrence of liver cancer. The cold, hard, dry and heavy salt of food can increase the risk of liver cancer, and more consumption of soy products and dairy products and regular consumption of vinegar can prevent liver cancer. Conclusion Liver cancer is closely related to the history of past liver disease, diet, drinking, smoking, and mental factors. Multi-edible soy products, dairy products and vinegar have the effect of preventing liver cancer.