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Abyssinone-V,4’-hydroxy-6,3’,5’-triprenylisoflavonone,abyssinone-VI和abyssinone-IV都是从刺桐中分离出来的天然双异戊烯基黄酮.利用简单、温和的方法首次完成了这4个天然产物的全合成.初步活性测试表明,4个化合物都具有一定的抑菌活性,其中,abyssinone-IV和abyssinone-V对金黄葡萄球菌和大肠杆菌都有良好的抑菌效果.所有新化合物的结构都经过HRMS,1H NMR和13C NMR确认.
Both Abyssinone-V, 4’-hydroxy-6,3 ’, 5’-triprenylisoflavonone, abyssinone-VI and abyssinone-IV are natural bis-prenylflavonoids isolated from Erythrina by the simple and gentle method The complete synthesis of the four natural products was completed.The preliminary activity test showed that all the four compounds had certain antibacterial activity, of which abyssinone-IV and abyssinone-V had good antibacterial activity against Staphylococcus aureus and Escherichia coli The structures of all new compounds were confirmed by HRMS, 1H NMR and 13C NMR.