肿瘤抑制蛋白maspin蛋白因在结直肠癌中与其他病理特征的紧密联系,以及对生存率和对辅助化疗敏感性的独立预测潜力而受到广泛重视。Fung CL、Chan C、Jankova L等对一组淋巴结阳性结肠癌连续病例的maspin蛋白表达、其他病理组织学特征以及术后生存率三者之间的关系进行探讨。收集1971～2001年期间450例有潜在可能行根治性切除淋巴结阳性结肠癌患者的病例资料,通过微点阵及免疫组化法检测其手术切除的肿瘤标本表面组织及深部组织的细胞核及细胞质中maspin The tumor suppressor protein maspin protein is widely recognized for its close association with other pathological features in colorectal cancer and its independent predictive potential for survival and sensitivity to adjuvant chemotherapy. Fung CL, Chan C, Jankova L and so on a group of consecutive cases of lymph node-positive maspin protein expression, other histopathological features and postoperative survival of the relationship between the three to explore. The data of 450 cases with potential resection of lymph node-positive colon cancer from 1971 to 2001 were collected. The micro-array and immunohistochemistry were used to detect the nuclear and cytoplasm of the surface and deep tissues of the resected tumor specimens maspin