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目的:观察贝那普利与氨氯地平联合治疗慢性肾脏病(CKD)合并高血压的疗效。方法:应用贝那普利与氨氯地平治疗50例CKD合并高血压患者,观察其治疗后降压效果、降低蛋白尿、保护肾功能水平,不良反应的发生情况,疗程4周。结果:贝那普利与氨氯地平联合治疗降压效果显著,降低蛋白尿,保护肾功能,患者耐受性及依从性好。结论:贝那普利与氨氯地平治疗CKD并高血压,具有良好的安全性和疗效性。
Objective: To observe the efficacy of benazepril and amlodipine in the treatment of chronic kidney disease (CKD) with hypertension. Methods: 50 patients with CKD and hypertension were treated with benazepril and amlodipine. The antihypertensive effect, proteinuria, renal function and adverse reactions were observed after 4 weeks of treatment. Results: The combination of benazepril and amlodipine was effective in lowering blood pressure, reducing proteinuria, and protecting renal function. Patient tolerance and compliance were good. Conclusion: Benazepril and amlodipine have good safety and curative effect in the treatment of CKD and hypertension.