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目的:观察中西医结合治疗慢性阻塞性肺疾病(COPD)合并肺动脉高压的临床效果。方法:将确诊为COPD且合并肺动脉高压的患者100例随机分为治疗组和对照组各50例,对照组应用抗炎、平喘、化痰及对症治疗,治疗组在对照组基础上加用自拟中药汤剂润肺活血汤口服,两组疗程均为1个月,统计对比两组患者治疗前后肺功能、证候积分、肺动脉压力、6 min步行试验的变化。结果:总显效率治疗组(88.0%)优于对照组(74.0%),P<0.05,有统计学意义;且降低肺动脉压力、提高6 min步行距离方面,治疗组优于对照组,P<0.05,有统计学意义。结论:中西医结合治疗慢性阻塞性肺疾病合并肺动脉高压患者的疗效确切,可改善患者的临床症状、降低肺动脉压力、提高生活质量。
Objective: To observe the clinical effect of integrated traditional Chinese and western medicine on chronic obstructive pulmonary disease (COPD) complicated with pulmonary hypertension. Methods: One hundred patients with COPD and pulmonary hypertension were randomly divided into treatment group (50 cases) and control group (50 cases). The control group was given anti-inflammatory, antiasthmatic, phlegm and symptomatic treatment. The treatment group Self-made herbal decoction Runfei Huoxue Tang oral administration of two groups were 1 month treatment, statistical comparison of two groups of patients before and after treatment of lung function, syndrome score, pulmonary artery pressure, 6 min walk test changes. Results: The total effective rate in the treatment group (88.0%) was superior to that in the control group (74.0%), P <0.05, with statistical significance. In reducing the pulmonary artery pressure and increasing the walking distance in 6 minutes, the treatment group was superior to the control group (P < 0.05, with statistical significance. Conclusion: Integrative treatment of chronic obstructive pulmonary disease with pulmonary hypertension in patients with exact effect, can improve the clinical symptoms of patients, reduce pulmonary artery pressure, improve quality of life.