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目的探讨新生儿低血糖症的高危影响因素及检测血清胰岛素的临床价值。方法选取医院收治的低血糖症足月新生儿70例作为低血糖组,取医院分娩的血糖正常足月新生儿68例作为正常组,检测两组新生儿的血糖水平,并分析娩出后低血糖症的危险因素。结果低血糖组新生儿娩出后12、24 h血清胰岛素水平及新生儿窒息缺氧、出生后感染、体质量<2 500 g或>4 000 g的发生率均明显高于正常组,差异均有统计学意义(均P<0.05);低血糖组产妇合并妊娠高血压综合征或糖尿病、乳汁分泌不足、溶血病史、吸烟史、体重指数(BMI)≥32 kg/m2的存在或发生率均明显高于正常组,差异均有统计学意义(均P<0.05)。结论临床应加强对新生儿血清胰岛素的检测,若存在异常及时行积极干预,降低低血糖症的发生率。
Objective To investigate the influencing factors of high risk of neonatal hypoglycemia and the clinical value of detecting serum insulin. Methods Seventy cases of full-term neonates with hypoglycemia in hospital were selected as hypoglycemia group. Sixty-eight full-term neonates with normal blood glucose in hospital were selected as the normal group. The neonatal blood glucose level was measured and the post-delivery hypoglycemia Disease risk factors. Results The hypoglycemia group at 12,24 h after delivery of serum insulin levels and neonatal asphyxia hypoxia, postnatal infection, the incidence of body mass <2 500 g or> 4 000 g were significantly higher than the normal group, the difference was Statistical significance (all P <0.05); the presence or the incidence of maternal hypoglycemia complicating pregnancy-induced hypertension syndrome or diabetes, lack of milk secretion, history of hemolytic disease, smoking history, body mass index (BMI) ≥32 kg / m2 Higher than the normal group, the difference was statistically significant (P <0.05). Conclusion Clinic should strengthen the detection of serum insulin in newborns, if there is abnormal and prompt intervention in a timely manner to reduce the incidence of hypoglycemia.