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目的:研究冠心病(CHD)伴阻塞性睡眠呼吸暂停低通气综合征(OSAHS)患者与单纯CHD患者心电的变化。方法:选取行24h动态心电图检测的单纯CHD患者42例(Ⅰ组),CHD伴OSAHS患者47例(Ⅱ组),对比分析Ⅰ组和Ⅱ组发生心律失常情况及心率变异性时域、频域指标,对其中室性期前收缩患者比较其窦性心率震荡指标。结果:房性心律失常和室性心律失常发生率Ⅱ组均明显高于Ⅰ组;Ⅱ组心率变异性时域指标SDNN[(91.51±16.43)∶(128.12±13.78)ms,P<0.05],SDANNI[(83.44±16.21)∶(117.32±17.68)ms,P<0.05],SDNNI[(33.15±9.89)∶(48.17±11.69)ms,P<0.05],均显著低于Ⅰ组;2组窦性心率震荡指标TO、TS值差异均有统计学意义(P<0.05)。结论:CHD伴OSAHS患者心律失常发生率明显增高,心率变异性显著降低,窦性心率震荡减弱。
Objective: To study the changes of ECG in patients with coronary heart disease (CHD) with obstructive sleep apnea-hypopnea syndrome (OSAHS) and simple CHD. Methods: Forty-two patients with CHD (group Ⅰ) and 47 patients with CHD accompanied by OSAHS (group Ⅱ) were enrolled in this study. The arrhythmia and heart rate variability in group Ⅰ and group Ⅱ were compared between time domain and frequency domain Indicators of ventricular contraction in patients whose ventricular sinus heart rate index compared. Results: The incidences of atrial arrhythmia and ventricular arrhythmia in group Ⅱ were significantly higher than those in group Ⅱ. The heart rate variability in group Ⅱ was SDNN [(91.51 ± 16.43): (128.12 ± 13.78) ms, P <0.05] [(83.44 ± 16.21) vs (117.32 ± 17.68) ms, P <0.05], SDNNI [(33.15 ± 9.89) :( 48.17 ± 11.69) ms, P <0.05] Heart rate turbulence indicators TO, TS values were significantly different (P <0.05). Conclusion: The incidence of arrhythmia in patients with CHD and OSAHS is significantly higher, heart rate variability is significantly lower, and sinus rhythm shock is weakened.