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环丙氟哌酸是一新的既可注射又可口服并具有优良抗菌活性的喹诺酮类广谱抗菌药。它除主要经肾脏消除外,肠道也可进行消除,故在粪便和肠粘液中能够达到较高浓度,这提示可以用于免疫损伤患者去除污染和感染的预防。然而已证明它能够抑制肝脏的药物代谢,能与茶碱、咖啡因、安替比林在药代动力学上发生相互作用。通过肝脏氧化酶系统进行代谢的免疫抑制剂环孢菌素,因其不良反应的发生与药物浓度关系甚大,
Ciprofloxacin is a novel quinolone broad-spectrum antibacterial that is both injectable and orally available and has excellent antibacterial activity. In addition to the main elimination by the kidneys, the intestine can also be eliminated, so in feces and intestinal mucus can reach higher concentrations, suggesting that the immune damage patients can be used to remove contamination and infection prevention. However, it has been shown to inhibit the liver’s pharmacokinetics and pharmacokinetics with theophylline, caffeine, and antipyrine. Cyclosporine, an immunosuppressant metabolized by the liver oxidase system, has a great relationship with drug concentration because of its adverse reaction.