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看了《世界科学》的白血病专题篇,非常喜欢。平素由于职业的原因,虽然接触大量医学专业文章,浏览《NATURE》等国际顶级科学期刊,但都是关注有哪个白血病相关的新基因、新途径、新药物被发现,而忽略了这些短小精悍的文章,通过深入浅出的语言,透过现象看本质,带给我们许多思考和启发。诚然,一些特定类型的白血病主要是由单个融合基因致病,诸如急性早幼粒细胞白血病(APL)、慢性粒细胞性白血病(CML)等等。使基于这些特征性融合基因的靶向治疗
I read the world science leukemia feature articles, I really like it. Usually due to occupational reasons, although exposure to a large number of medical professional articles, browse “NATURE” and other top international scientific journals, but are concerned about which leukemia-related new genes, new ways, new drugs were found, while ignoring these short and hard articles , Through profound language in simple language, through the phenomenon to see the essence, give us many thoughts and inspiration. Indeed, some specific types of leukemia are primarily caused by a single fusion gene, such as acute promyelocytic leukemia (APL), chronic myelogenous leukemia (CML) and the like. Targeted therapies based on these characteristic fusion genes