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目的以调查住院病人为基础了解中山市华支睾吸虫感染状况和流行特征。方法 2016年,以中山市23个镇区医院作为监测医院,以监测医院住院病人中在中山市居住时间超过6个月者作为监测对象,采集其粪便标本,采用改良加藤厚涂片法检查华支睾吸虫虫卵,根据中山市2016年常住人口年龄和性别构成对调查得到的华支睾吸虫感染率进行标化,对不同镇区及合并相关疾病者感染率进行分析。结果共2 667人纳入监测,镜检阳性219人,感染率为8.21%。镜检阳性人群中,男性179例,占81.74%;年龄最小4岁,最大89岁,平均(62.20±13.80)岁。经年龄和性别标化后,中山市全人群感染率为3.62%,其中男性感染率为5.46%,女性为1.53%,男性是女性的3.57倍。男、女性均呈现出年龄越大感染率越高的趋势(χ_(男性)~2=99.91、χ_(女性)~2=16.51,P均<0.01)。镇区标化感染率最高为10.40%,最低为0,呈北高南低的特征。胆结石病人标化感染率为9.22%,非胆结石病人为3.40%,前者是后者的2.71倍。结论 30岁以上、患有胆结石及居住于高感染率镇区者是中山市华支睾吸虫病防控的重点人群。
OBJECTIVE To understand the prevalence and epidemic characteristics of Clonorchis sinensis in Zhongshan City based on the investigation of inpatients. Methods In 2016, 23 township hospitals in Zhongshan City were used as monitoring hospitals to monitor the hospitalization of patients in Zhongshan City living in the city for more than 6 months as a monitoring object, the stool specimens were collected, using modified Kato thick smear method to check the Chinese Clonorchis sinensis eggs, according to the Zhongshan population in 2016 by the age and sex composition of the survey population were normalized Clonorchis sinensis infection rate, infection rates in different towns and associated diseases were analyzed. Results A total of 2 667 people were included in the surveillance, and 219 were positive for microscopic examination. The infection rate was 8.21%. Among the positive microscopic examination, there were 179 males (81.74%), the youngest was 4 years old and the oldest was 89 years old, with an average of (62.20 ± 13.80) years old. After standardized by age and sex, the overall infection rate in Zhongshan was 3.62%, of which the male infection rate was 5.46%, the female was 1.53% and the male was 3.57 times of the female. Both male and female showed a trend of higher infection rate (χ_ (male) ~ 2 = 99.91, χ_ (female) ~ 2 = 16.51, P <0.01). The highest standardization of township infection rate was 10.40%, the lowest is 0, showing the characteristics of high north to south. Gallstone patients standardized infection rate was 9.22%, non-gallstone patients was 3.40%, the former is 2.71 times the latter. Conclusions People over 30 years old with gallstones and living in high infection rate township are the key population of prevention and control of Clonorchis sinensis in Zhongshan City.