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目的探讨尿沉渣定量分析仪联合尿干化学分析仪在尿液细胞检测中的应用价值。方法 500例住院患者,采用sysmex UF-500i、AX4030和离心沉渣镜检对尿液标本进行检测,以沉渣镜检结果为金标准,分析sysmex UF-500i、AX4030在尿液细胞检测中的诊断价值。结果三种检测方法阳性检出率比较差异无统计学意义(P>0.05)。sysmex UF-500i检测白细胞(WBC)的特异度、敏感度和准确度分别为86.96%、80.65%和85.00%;AX4030检测WBC的特异度、敏感度和准确度分别为87.25%、80.00%和85.00%;sysmex UF-500i检测红细胞(RBC)的特异度、敏感度和准确度分别为91.78%、79.59%和88.20%;AX4030检测RBC的特异度、敏感度和准确度分别为92.07%、80.27%和88.60%;sysmex UF-500i+AX4030检测WBC的特异度、敏感度和准确度分别为95.65%、90.32%和94.00%;sysmex UF-500i+AX4030检测RBC的特异度、敏感度和准确度分别为97.17%、93.20%和96.00%。sysmex UF-500i和AX4030联合检测的特异度、敏感度和准确度明显高于单一sysmex UF-500i或AX4030检测,差异有统计学意义(P<0.05)。结论尿沉渣定量分析仪联合尿干化学分析仪在尿液细胞检测中能显著提高特异度、敏感度和准确度,为临床诊断和治疗提供可靠的依据。
Objective To investigate the value of urine sediment quantitative analyzer combined with urinary dry chemical analyzer in urine cell detection. Methods 500 hospitalized patients were tested for urinalysis by urine microscopy using the sysmex UF-500i, AX4030 and centrifugal sediment microscopy. The diagnostic value of the sysmex UF-500i and AX4030 in urinalysis . Results There was no significant difference in positive detection rate among the three detection methods (P> 0.05). The specificity, sensitivity and accuracy of sysmex UF-500i in detecting WBC were 86.96%, 80.65% and 85.00%, respectively. The specificity, sensitivity and accuracy of AX4030 in detecting WBC were 87.25%, 80.00% and 85.00, respectively %. The specificity, sensitivity and accuracy of the detection of RBC by sysmex UF-500i were 91.78%, 79.59% and 88.20% respectively. The specificity, sensitivity and accuracy of AX4030 for detection of RBC were 92.07% and 80.27% And 88.60%, respectively. The specificity, sensitivity and accuracy of sysmex UF-500i + AX4030 for detecting WBC were 95.65%, 90.32% and 94.00% respectively. The sensitivity, specificity and specificity of sysmex UF-500i + AX4030 for detecting RBC were respectively 97.17%, 93.20% and 96.00% respectively. The specificity, sensitivity and accuracy of the combination of sysmex UF-500i and AX4030 were significantly higher than those of single sysmex UF-500i or AX4030 (P <0.05). Conclusion Urine sediment quantitative analyzer combined with urinary dry chemical analyzer can significantly improve the specificity, sensitivity and accuracy in urine cell detection, and provide a reliable basis for clinical diagnosis and treatment.