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皮肌炎(DM)是一种自身免疫性疾病,以肌肉无力、疼痛、皮肤红斑等为主要临床表现,可累及肺、心和胃肠道等器官。部分病人并发吞咽困难,不能经口进食,若不及时给予合理的营养支持治疗,可出现营养不良,影响疾病的转归。我院于2009年7月12日收住了1例皮肌炎并发吞咽困难的病人,营养治疗过程中发现病人能很好地耐受短肽型或以大豆蛋白为氮源的整蛋白型肠内营养(EN)制剂,而以牛奶蛋白为氮源的整蛋白型EN制剂却不耐受,现报道如下。
Dermatomyositis (DM) is an autoimmune disease characterized by muscular weakness, pain and skin erythema, which can affect organs such as lung, heart and gastrointestinal tract. Some patients complicated by swallowing difficulties, can not be oral intake, if not promptly given a reasonable nutritional support and treatment, malnutrition may occur, affecting the outcome of the disease. Our hospital in July 12, 2009 admitted to a case of dermatomyositis complicated with dysphagia in patients with nutritional therapy found that patients can well tolerate the short peptide or soy protein as a source of the whole protein-type intestine Endo-nutrition (EN) preparations, which are not tolerant to the whole protein EN formulation with milk protein as a nitrogen source, are reported below.