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目的:应用液基超薄细胞技术(Thinprep Cytologic Test,TCT)和Bethesda系统(TBS)对2454例患者进行检测,了解该地区宫颈病变现状。方法:2008年1月至2010年6月梅城地区共2 454例女性患者接受TCT检查及TBS细胞学分类诊断,TCT检查异常患者进行阴道镜病理检查,统计结果并进行分析。结果:(1)2 454例涂片中异常涂片425例(17.33%),其中良性反应性改变227例(9.26%),不典型鳞状细胞(ASCUS)86例(3.50%),低度鳞状上皮内病变(LSIL)73例(2.98%),高度鳞状上皮内病变(HSIL)37例(1.51%),鳞状细胞癌(SCC)1例(0.04%),子宫内膜腺癌1例(0.04%),人乳头瘤病毒(HPV)94例(3.83%);(2)不同年龄段宫颈上皮细胞患病率,最高为≤25岁组,占10.46%(25/239),其次为≥56岁组,占8.69%(10/115);(3)TCT与阴道镜的符合率分别为68.21%、64.90%。结论:扩大该地区宫颈癌普查范围,加强对年轻妇女宫颈癌知识的普及。
Objective: To investigate the status of cervical lesions in 2454 patients by Thinprep Cytologic Test (TCT) and Bethesda system (TBS). Methods: From January 2008 to June 2010, a total of 2 454 female patients in Meicheng district were diagnosed by TCT and TBS cytology. Colposcopy was performed on patients with abnormal TCT and the results were analyzed. Results: (1) There were 425 cases (17.33%) with abnormal smear in 2 454 smears, of which 227 cases (9.26%) had benign reactivity, 86 cases (3.50%) had atypical squamous cells (ASCUS) There were 73 cases (2.98%) of squamous intraepithelial lesion (LSIL), 37 cases (1.51%) of high grade squamous intraepithelial lesion (HSIL), 1 case of squamous cell carcinoma (SCC) 1 case (0.04%), and 94 cases (3.83%) of human papillomavirus (HPV). (2) The prevalence of cervical epithelial cells in different age groups was up to 10.46% (25/239) Followed by ≥56 years old, accounting for 8.69% (10/115). (3) The coincidence rates of TCT and colposcopy were 68.21% and 64.90% respectively. Conclusion: Expand the scope of the census of cervical cancer in the region and strengthen the popularization of knowledge about cervical cancer among young women.