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本文报导近四年来观察的25例高白细胞性粒细胞性白血病时出现的呼吸困难,其中21例为急粒,其白细胞总数为125,000～450,000/mm~3(平均245,000),周围血原粒细胞>80%;另4例为慢粒急变患者,其白细胞总数为135,000～540,000/mm~3(平均395.000),原粒细胞占35～80%。6例于入院时即有呼吸困难,其他病例在入院后数小时内发生,每分钟呼吸数都在40次以上,且呼吸困难与白细胞迅速增高同时出现,但听诊并无异常。心脏除有心动过速外,未见其他明显改变。肺部X线检查有结节性和/或絮状弥漫性阴影。25例中11例有
This article reports on the dyspnea observed in 25 cases of ALL with leukemia observed in the past four years, 21 of which are acute particles with a total leukocyte count of 125,000 to 450,000 / mm 3 (average 245,000). Peripheral blood neutrophils > 80%. In the other 4 cases, the total number of leukocytes was 135,000 ~ 540,000 / mm ~ 3 (average 395.000) and the number of myeloblasts was 35 ~ 80%. Six patients had dyspnea on admission. Other cases occurred within a few hours after admission. The number of breaths per minute was more than 40, and dyspnea was accompanied by the rapid increase of leukocytes. However, there was no abnormality in auscultation. In addition to heart tachycardia, no other significant changes. Pulmonary X-ray examination has nodular and / or flocculent diffuse shadow. Of the 25 cases, 11 had