目的:选择6个月内重症监护室收治的所有重症胰腺炎4例,暴发性胰腺炎1例,入科后积极补液、抗感染、腹腔渗夜引流或外科开腹手术、营养及脏器支持等治疗对预后影响。结论:前期治疗及时、正确,选用合理抗生素后一般病人可出现好转,血流动力学较稳定,但后期疾病发展,随细菌向革兰氏阳性菌及真菌转变,感染及营养状态逐渐恶化,多个脏器功能损害,病情恶化,虽多种治疗方案联合应用,疗效不佳,需有待研究。 PURPOSE: To select 4 patients with severe pancreatitis admitted to intensive care unit within 6 months, 1 case of fulminant pancreatitis, active rehydration, antiinflammatory, peritoneal drainage or surgical laparotomy, nutrition and organ support Other treatment effects on prognosis. CONCLUSIONS: The early treatment is prompt and correct. After the rational antibiotics are used, the general patients may have better hemodynamics, but the disease develops later. With the change of bacteria to Gram-positive bacteria and fungi, the infection and nutrition status gradually worsen, and more Organ dysfunction, deterioration, although a variety of treatment options combined with poor efficacy, need to be studied.