保留肾单位手术(NSS),特别是腹腔镜下或机器人辅助腹腔镜下的NSS,成为近年来局限性肾细胞癌(RCC)治疗的主流术式.在治疗局限性RCC的众多NSS中主要关注三个问题,即最大限度地减少热缺血时间,保护正常肾脏功能;完整切除肿瘤,降低切缘阳性率;减少并发症.其中如何最大限度地减少热缺血对保留的肾脏功能的损害是目前该领域学者关注的热点之一,本文就此做一综述.“,”Nephron sparing surgery (NSS),especially laparoscopic or robot assisted laparoscopic NSS,has become one of the main surgeries to treat localized renal cell carcinoma in recent years.There are three questions (trifecta outcome) during many NSS surgeries in the treatment of localized renal cell carcinoma,namely,minimizing the warm ischemia time to protect renal function,completely excising tumor to reduce the positive margin rate and reducing the complications.How to maximumly preserve the nephron from warm ischemia has become the hotspot in this field at present,so this article will give a detailed explanation.