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目的探讨氯胺酮与芬太尼在人流镇痛中的效果。方法对于本院近年来收治的愿意作人流术的196例行无痛人流术,随机将其分为2组,A组用微量氯胺酮,B组用微量芬太尼。以异丙酚麻醉,术中观察2组血压,心率,呼吸及术中不良反应。记录麻醉时间,苏醒时间及异丙酚的用量。结果微量氯胺酮与芬太尼都能增强异丙酚的作用,但芬太尼同时也增加其对循环,呼吸的抑制作用,而氯胺酮与其配伍能减少副作用,术中,术后循环,呼吸较稳定。结论氯胺酮和芬太尼用于人流镇痛均安全,有效,与异丙酚联合应用,其麻醉效果好,但芬太尼有抑制循环和呼吸的作用,使用时需观察血压和呼吸变化。
Objective To investigate the effect of ketamine and fentanyl on abortion. Methods A total of 196 patients who were willing to make abortion in our hospital in recent years were randomly divided into two groups: A group with trace ketamine and B group with trace Fentanyl. To propofol anesthesia, intraoperative observation of two groups of blood pressure, heart rate, respiration and intraoperative adverse reactions. Record anesthesia time, recovery time and the amount of propofol. Results Both trace ketamine and fentanyl enhanced the effect of propofol, but fentanyl also increased its inhibitory effect on circulation and respiration. However, ketamine combined with fentanyl reduced side effects, and intraoperative and postoperative circulation and respiration were stable . Conclusions Both ketamine and fentanyl are safe and effective for the treatment of abortion and analgesia. Combined with propofol, ketamine and fentanyl have good anesthetic effects. However, fentanyl can inhibit circulation and respiration, and blood pressure and respiratory changes should be observed when used.