一般认为甲胎蛋白(AFP)作为一种特异性强的肿瘤生物标志物,具有鉴别诊断原发性肝癌与转移性肝癌以及非癌肝病的应用价值,但多年临床实践发现其仍有一定的局限性。为提高对原发性肝癌诊断的准确性,1988～1991年本文通过AFP、癌胚抗原(CEA)和血清铁蛋白(SF)联合检测,以探讨其对肝脏良恶性疾病的鉴别诊断意义。 Alpha-fetoprotein (AFP) is generally considered as a specific tumor biomarker and has the application value in the differential diagnosis of primary liver cancer, metastatic liver cancer and non-cancerous liver disease, but it has been found to have certain limitations for many years of clinical practice. Sex. In order to improve the accuracy of the diagnosis of primary liver cancer, from 1988 to 1991 this article through the joint detection of AFP, carcinoembryonic antigen (CEA) and serum ferritin (SF) to explore its differential diagnosis of benign and malignant liver disease.