目的:报道5例女性生殖器官非霍奇金淋巴瘤,其中1例原发性子宫体非霍奇金淋巴瘤伴子宫内膜浆液性腺癌为国内首例及文献第7例报道,由此提供了有价值的病理文献资料。方法:按AnnArbor淋巴瘤临床分期及WHO(1997)组织学分类,分析临床症状,病理检查,免疫表型及预后。结果:5例患者年龄33～60岁。肿瘤分别位于卵巢(1例),子宫体(2例)及宫颈(2例)。免疫表型4例为B细胞性,1例为T细胞性。除2例于1年内死亡外,余3例随访4～4年6个月均生存。结论:女性生殖器官病理标本的各不同解剖部位均应分别取材,否则容易遗漏病变,术中应详细探查肿瘤范围,方能确定肿瘤的临床分期及原或继发性。患者应采取有效治疗,虽已有局部扩散,仍有机会获得较好预后。 OBJECTIVE: To report five cases of female genital NHL, of which one case of primary uterine non-Hodgkin’s lymphoma with endometrial serous adenocarcinoma was reported in the first case and reported in the seventh case, thus providing The valuable pathological literature. Methods: According to the clinical stage of Ann Arbor lymphoma and WHO (1997) histological classification, clinical symptoms, pathological examination, immunophenotype and prognosis were analyzed. Results: Five patients were 33 to 60 years old. The tumors were located in ovary (1 case), uterus (2 cases) and cervix (2 cases). Immunophenotype 4 cases of B cell, 1 case of T cell. Except 2 cases died within 1 year, 3 cases were followed up for 4 to 4 years and 6 months. Conclusion: The different anatomical parts of female genital pathology specimens should be drawn separately, otherwise it is easy to miss the lesion, the tumor should be explored in detail during surgery to determine the clinical stage of the tumor and the original or secondary. Patients should take effective treatment, although there have been local proliferation, still have the opportunity to obtain a better prognosis.