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目的研究急性冠脉综合征(ACS)患者的血脂特点及脂蛋白a(Lp(a))的相关性。方法对85例ACS患者的总胆固醇(TC)、甘油三酯(TG)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)、载脂蛋白A-I(ApoA)、载脂蛋白B(ApoB)、Lp(a)的含量进行测定,并与40例稳定性心绞痛(SA)患者比较,分析Lp(a)与血脂因素的相关性。结果ACS组TC、TG、LDL-C明显升高,血清Lp(a)浓度高于SA组(P<0.001)。ACS组血清Lp(a)水平与血脂各指标无明显相关性(P>0.10)。结论急性冠脉综合征存在血脂代谢紊乱,但Lp(a)含量与血脂因素没有相关性。
Objective To study the relationship between serum lipids and lipoprotein a (Lp (a)) in patients with acute coronary syndrome (ACS). Methods The total cholesterol (TC), triglyceride (TG), high density lipoprotein cholesterol (HDL-C), low density lipoprotein cholesterol (LDL-C), apolipoprotein AI (ApoA) The levels of ApoB and Lp (a) were determined and compared with those of 40 patients with stable angina (SA). The correlation between Lp (a) and lipids was analyzed. Results The levels of TC, TG and LDL-C in ACS group were significantly higher than those in SA group (P <0.001). Serum Lp (a) level in ACS group had no significant correlation with each index of blood lipid (P> 0.10). Conclusion Acute coronary syndromes have dyslipidemia, but the content of Lp (a) has no correlation with the level of lipids.