本文分析1951～1979年首都医院190例肢端肥大症的临床表现,着重探讨病情活动指标:1)肢端肥大:仅60％左右病例具备本病临床及X线表现,骨、软骨及软组织的过度生长只表明曾受生长激素(hGH)过度作用,不能说明病情是否活动;2)体重超重:176例中96例体重超重20％以上,超重20％以上例数随蝶鞍增大程度而增加;3)蝶鞍改变:176例中蝶鞍正 This article analyzes the clinical manifestations of 190 cases of acromegaly at the Capital Hospital from 1951 to 1979, and focuses on the indicators of disease activity: 1) Acromegaly: Only 60% of cases have clinical and X-ray findings of the disease, bone, cartilage and soft tissue. Overgrowth only indicates that it has been overactive by growth hormone (hGH) and cannot explain whether the disease is active or not; 2) Overweight: 96 cases of 176 cases of overweight over 20%, overweight over 20% increase in the number of cases with increase in sella ;3) Sella changes: 176 cases of sella