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目的 探讨充血性心力衰竭 (CHF)与免疫功能变化情况 .方法 测定了 46例CHF患儿及 5 0例健康儿童T淋巴细胞亚群、T淋巴细胞转化率、免疫球蛋白及补体 (C3 )作分析比较 .结果 CHF组CD3 、CD4 、CD8、CD4 /CD8、T淋巴细胞转化率均显著降低 ,而IgG、C3 升高 .结论 CHF患儿影响细胞免疫功能 ,并可激活补体系统 ,造成免疫损伤 ,加重心功能不全
Objective To investigate the changes of congestive heart failure (CHF) and immune function.Methods T lymphocyte subsets, T lymphocyte transformation rate, immunoglobulin and complement (C3) in 46 CHF children and 50 healthy children were measured Results The results showed that the conversion rates of CD3, CD4, CD8, CD4 / CD8 and T lymphocytes in CHF group were significantly decreased, while the levels of IgG and C3 were significantly increased in CHF group.Conclusion CHF patients can affect cellular immune function and activate complement system, resulting in immune damage , Increase heart dysfunction