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目的观察环磷腺苷葡胺治疗老年心肌梗死后心功能不全的临床疗效。方法将36例老年心肌梗死后心功能不全患者随机分为治疗组和对照组各18例。对照组行常规综合治疗,治疗组则在常规综合治疗基础上加用环磷腺苷葡胺治疗,比较2组疗效和血浆脑钠肽水平。结果治疗组总有效率为94.4%高于对照组的72.2%,差异有统计学意义(P<0.05)。治疗前2组血浆脑钠肽水平比较差异无统计学意义(P>0.05),治疗后2组血浆脑钠肽水平均低于治疗前,且治疗组低于对照组,差异均有统计学意义(P<0.05)。结论环磷腺苷葡胺治疗老年心肌梗死后心功能不全的临床疗效肯定,值得借鉴。
Objective To observe the clinical efficacy of cyclic adenosine monophosphate (AMPA) in the treatment of cardiac insufficiency after senile myocardial infarction. Methods 36 cases of elderly patients with myocardial infarction after myocardial infarction were randomly divided into treatment group and control group of 18 cases. The control group underwent routine comprehensive treatment. The treatment group was treated with cyclic adenosine monophosphate (AMPA) on the basis of conventional comprehensive treatment. The curative effect and plasma BNP level were compared between the two groups. Results The total effective rate of the treatment group was 94.4% higher than that of the control group (72.2%), the difference was statistically significant (P <0.05). There was no significant difference in plasma brain natriuretic peptide levels between the two groups before treatment (P> 0.05). After treatment, the levels of plasma brain natriuretic peptide in both groups were lower than before treatment, and the treatment group was lower than the control group, the difference was statistically significant (P <0.05). Conclusion CAMP is effective in treating cardiac insufficiency after myocardial infarction in elderly patients and is worth learning from.