论文部分内容阅读
目的调查保健门诊儿童血铅水平以及铅中毒状况。方法采用阳极溶出伏安(ASV)法,检测4385例1个月～18岁儿童的血铅水平,并比较不同年龄组男、女童的血铅水平及其季节特点和临床特征。结果本组儿童血铅水平为(55.9±7.5)μg/L,男、女童血铅水平分别为(59.1±7.4)μg/L、(50.5±7.4)μg/L。血铅水平≥100μg/L者695例,占15.8%,其中男童506例,检出率18.0%;女童189例,检出率11.9%,两者比较P<0.001。不同年龄组儿童铅水平升高和铅中毒检出率随着年龄增长而增加,其铅中毒程度有明显差别,轻度铅中毒与年龄呈正相关(线性回归系数B=9.348389E-03),中度和重度铅中毒与年龄呈负相关(线性回归系数B=-9.348432E-03)。1岁以内中和重度铅中毒者占45.5%;儿童血铅水平、铅中毒率有明显的季节特点[CHI(M-EXT)=8.982P总<0.001],夏秋季节铅水平和铅中毒检出率显著增高。结论男童铅中毒检出率高于女童。儿童铅水平和铅中毒检出率随年龄增长而增加,但铅中毒程度与年龄呈负相关。夏秋季血铅水平高于冬春季。
Objective To investigate the level of blood lead in health outpatient clinics and lead poisoning. Methods The blood lead levels of 4385 children aged 1 month to 18 years were measured by anodic stripping voltammetry (ASV). The blood lead levels, seasonal characteristics and clinical features of boys and girls in different age groups were compared. Results The level of blood lead was (55.9 ± 7.5) μg / L in this group, and (59.1 ± 7.4) μg / L and (50.5 ± 7.4) μg / L respectively in boys and girls. Blood lead levels ≥ 100μg / L in 695 cases, accounting for 15.8%, of which 506 cases of boys, the detection rate was 18.0%; girls 189 cases, the detection rate was 11.9%, both P <0.001. The levels of lead in children of different ages increased and the detection rate of lead poisoning increased with age. There was a significant difference in the degree of lead poisoning. Mild lead poisoning was positively correlated with age (linear regression coefficient B = 9.348389E-03) Degree and severe lead poisoning were negatively correlated with age (linear regression coefficient B = -9.348432E-03). Children aged less than 1 year accounted for 45.5% of moderate lead poisoning; children’s blood lead level and lead poisoning rate had obvious seasonal characteristics [CHI (M-EXT) = 8.982P total <0.001], summer and autumn lead levels and lead poisoning were detected The rate was significantly higher. Conclusion The detection rate of lead poisoning in boys is higher than that in girls. Child lead levels and lead poisoning detection rate increased with age, but the degree of lead poisoning was negatively correlated with age. Blood lead levels in summer and autumn are higher than in winter and spring.