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幽门螺杆菌(H.pylori)感染和消化性溃疡、胃癌的密切联系要求建立一种针对此种感染的非创伤性检测方法。目前常用的是血清IgG检测。H.pylori的特异性抗体出现于胃液、尿液和唾液中。唾液腺主要产生IgA,而IgG和IgM则来自血液渗出至齿龈间的液体中。采集唾液标本比血液能广泛采样和邮寄。本文EIISA试剂盒测定了唾液中特异性H.py-lori IgG,并比较了唾液内IgG和IgA,唾液IgG和血清IgG检测用于诊断H.Pylori感染的优劣。并通过检测唾液内IgG评估了摄入非类固醇类抗炎性药物(NSA/DS)的45岁以下消化不良病人在内窥镜检查前的过筛情况。
The close relationship between H. pylori infection and peptic ulcer and gastric cancer requires establishing a non-invasive detection method for this infection. Currently used is the serum IgG test. Specific antibodies to H. pylori appear in gastric juice, urine and saliva. The salivary glands produce predominantly IgA, while IgG and IgM come from the exudation of blood into the fluid between the gingiva. Collect saliva samples that can be widely sampled and mailed over blood. The EIISA kit was used to determine the specificity of H.py-lori IgG in saliva and to compare the detection of IgG and IgA in saliva, salivary IgG and serum IgG for the diagnosis of H.pylori infection. And screening for salivary IgG to assess screening of dyspepsia patients under 45 years of age prior to endoscopy for non-steroidal anti-inflammatory drugs (NSA / DS).