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目的:探讨安定,葡萄糖酸钙静推,配合小剂量缩宫素静滴,在足月妊娠引导中临床应用价值。方法:选取我院2013年4月1日-2013年5月31日足月待产孕妇应用药物药物引产的100例,分为A组(缩宫素组)68例,B组(地诺前列酮组)32例,所有孕妇宫颈评分均≤5分,年龄、孕周、孕产次无明显差异,无使用药物禁忌症,无试产禁忌症,A组住院当天给予安定10mg,葡萄糖酸钙10ml,静推0.2%的缩宫素,静滴(1.0U+5%G.S500ml),次日常规0.5%缩宫素静滴(2.5U+5%G.S500ml)8-30滴/分,6h未诱导出规律宫缩停药,连续3天无效,用药失败。B组住院次日给予地诺前列酮栓10mg,阴道放置,栓剂拉绳置于阴道口,如有宫缩过强、破膜、临产、24h未诱导规律宫缩取出。结果:两组阴道分娩率,新生儿窒息率差异无统计学意义(P>0.05)缩宫素组产后2h出血量(200±50)ml,急产率、胎儿窘迫率明显低于地诺前列酮组,差异有统计学意义(P<0.05)。结论:安定,葡萄糖酸钙静推配合小剂量缩宫素静滴在足月妊娠引产中具有价格便宜,疼痛程度轻(多在无痛状态下宫颈成熟),产后出血少,急产少、胎儿窘迫少等优点,值得临床推广应用。
Objective: To investigate the clinical value of diazepam and calcium gluconate in combination with low-dose oxytocin intravenous infusion in term pregnancy guidance. Methods: A total of 100 pregnant women with full-term expectant mothers were induced abortion from April 1, 2013 to May 31, 2013. The patients were divided into group A (oxytocin group) 68 cases, group B (dinoprostone Group) 32 cases, all pregnant women cervical score ≤ 5 points, no significant difference in age, gestational age, pregnancy and childbirth, no drug contraindications, no trial contraindications, A group on the day of hospitalization given diazepam 10mg, calcium gluconate 10ml , Intravenous (1.0U + 5% G.S500ml), 0.5% oxytocin intravenous infusion (2.5U + 5% G.S500ml) 8-30 drops / 6h did not induce a regular uterine withdrawal, 3 consecutive days invalid, medication failed. Group B was given dirprost the second day of hospitalization suppository plug 10mg, vaginal placement, suppository drawstring placed in the vaginal opening, if uterine contractions too strong, rupture of membranes, labor, 24 hours did not induce the law of contractions removed. Results: There was no significant difference in vaginal delivery rate and neonatal asphyxia between the two groups (P> 0.05). The oxytocin group had a blood loss of 200 ± 50 ml at 2 hours postpartum, and the rate of acute birth and fetal distress was significantly lower than that of dinotech Ketone group, the difference was statistically significant (P <0.05). CONCLUSIONS: The combination of diazepam and calcium gluconate with low-dose oxytocin intravenously has the advantages of cheap price, mild pain (mostly cervical ripening in painless state), less postpartum hemorrhage, less emergency labor and fetuses Less distress and other advantages, it is worth promoting clinical application.