论文部分内容阅读
目的研究放射性125I粒子源治疗前列腺癌的剂量分布。方法采用三维治疗计划系统(3-DTPS)进行实验模拟,前列腺癌用肿瘤模型代替,应用热释光剂量学方法,模拟测量前列腺癌中的剂量分布。结果实验表明,125I粒子源治疗前列腺癌是在不均匀剂量模式下受照,剂量直接与粒子源的数量和几何位置有关。结论125I粒子源表面剂量最高,随着距离增加而剂量迅速下降。粒子源的间距越小瘤内剂量越高。
Objective To study the dose distribution of radioactive 125I particle source in the treatment of prostate cancer. Methods Three-dimensional treatment planning system (3-DTPS) was used to simulate the experiment. The prostate cancer was replaced by a tumor model. The dose distribution in prostate cancer was simulated by thermoluminescence dosimetry. Results Experiments have shown that 125I particle source treatment of prostate cancer is irradiated in an inhomogeneous dose pattern and the dose is directly related to the number of particle sources and geometric positions. Conclusion The dose of 125I particle source is the highest, and the dose decreases rapidly with the increase of distance. The smaller the distance between particle sources, the higher the intratumoral dose.