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目的探讨运动饮食干预配合胰岛素与沙格列汀治疗2型糖尿病对患者生活质量的影响。方法将200例2型糖尿病患者随机分为试验组和对照组各100例。所有患者均给予胰岛素、沙格列汀等糖尿病常规治疗药物。试验组患者根据其身体条件、病情程度额外给予针对性饮食干预和运动锻炼措施,对照组不给予。2组连续治疗3个月,比较2组临床疗效、血糖控制水平,并评价生活质量。结果试验组总有效率为96.00%明显高于对照组的83.00%,差异有统计学意义(P<0.05)。治疗前2组FPG,2h PG和餐后最高血糖水平差异均无统计学意义(P>0.05)。治疗后2组患者各项血糖指标均有所降低,且试验组患者降低幅度大于对照组,差异均有统计学意义(P<0.05)。试验组生活质量水平高于对照组,差异均有统计学意义(P<0.05)。结论运动饮食干预配合胰岛素与沙格列汀治疗可有效降低2型糖尿病患者血糖水平,提高其治疗效果和生活质量。
Objective To investigate the effect of exercise and diet intervention with insulin and saxagliptin on quality of life in patients with type 2 diabetes. Methods 200 patients with type 2 diabetes were randomly divided into experimental group and control group of 100 cases. All patients were given insulin, saxagliptin and other conventional diabetes drugs. Patients in the test group were given additional dietary intervention and exercise training measures based on their physical condition and severity of illness, but not in the control group. Two groups of continuous treatment for 3 months, compared the clinical efficacy of two groups, the level of blood glucose control, and evaluation of quality of life. Results The total effective rate was 96.00% in the experimental group was significantly higher than 83.00% in the control group, the difference was statistically significant (P <0.05). There were no significant differences in FPG, 2h PG and the highest postprandial blood glucose level before treatment (P> 0.05). After treatment, the blood glucose of the two groups of patients were reduced, and the reduction rate of the experimental group was greater than that of the control group, the difference was statistically significant (P <0.05). The quality of life of the experimental group was higher than that of the control group, the differences were statistically significant (P <0.05). Conclusion Exercise and diet interventions combined with insulin and saxagliptin can effectively reduce the blood sugar level in type 2 diabetic patients and improve their therapeutic effect and quality of life.