目的　观察肝能滴丸对小鼠试验性肝损伤的保护作用,评价保肝降酶作用。方法　采用化学毒物四氯化碳(CCl4)致小鼠肝脏损伤,测定其生化指标并观察病理组织学改变。结果　肝能滴丸0 .2 34、0 .117g·kg-1均能显著降低CCl4肝损伤所致的小鼠血清谷丙转氨酶(ALT)和谷草转氨酶(AST)升高(P <0 .0 1)。结论　结果表明,肝能滴丸对小鼠试验性肝损伤具有明显的保护作用。 Objective To observe the protective effect of Ganneng Dripping Pills on experimental hepatic injury in mice and evaluate the effects of protecting liver and reducing enzymes. Methods Hepatic injury in mice was induced by chemical poison carbon tetrachloride (CCl4). The biochemical indexes were measured and histopathological changes were observed. RESULTS: The liver energy dropping pills 0.234, 0.117 g·kg-1 all significantly reduced the serum ALT and AST levels in mice with CCl4 liver injury (P < .0 1). Conclusions The results show that Ganneng Dripping Pill has obvious protective effect on experimental liver injury in mice.